SSRI (Selective serotonin reuptake inhibitors) is a type of antidepressant traditionally used to treat anxiety and depressive disorders. Since some patients using SSRIs complained of a delay in ejaculation, some researchers in the early 90s developed an interest for its potential as a treatment for premature ejaculation. Nowadays, doctors can prescribe SSRIs as an off-label […]
Physiology

Dapoxetine for Premature Ejaculation Review
Dapoxetine is an ejaculation-delaying drug effective against premature ejaculation. You can find it under several names such as Priligy and Westoxetin. First developed as an antidepressant, it isn’t used to treat depression because the body evacuates the drug rapidly. However, it’s a good treatment option for premature ejaculation since it allows the ejaculation delay effects of an SSRI without having […]

Clomipramine for Premature Ejaculation
Clomipramine is an antidepressant from the tricyclic family (TCA). It is also one of the first drugs tested for its effect on premature ejaculation. While it has some ejaculation delaying effect, it’s not an approved drug for the treatment of premature ejaculation. Even as an off-label solution, SSRIs are better options for treating premature ejaculation since […]

Refractory Period and Premature Ejaculation
What is the refractory period? The refractory period is a stage a man enters after ejaculating. During this period, it’s more difficult for him to get aroused. Therefore, erections are more difficult to gain. When a man achieves an erection during his refractory period, it will be a softer erection. It can also be tougher […]

PC Muscles and Premature Ejaculation
What are PC Muscles? The PC muscles (pubococcygeal muscles) are a series of muscles situated between your pubic bone and coccyx. In simpler term, it’s the muscles that sit between your anus and your testicles. They are used, among other things, to controls urine flow when you urinate. If you try to stop peeing once it stated, that’s your PC […]